The Impact of Single-Cell Genomics on Adipose Tissue Research.
Deutsch A, Feng D, Pessin JE, Shinoda K.Int J Mol Sci. 2020 Jul 5;21(13):4773. doi: 10.3390/ijms21134773.PMID: 32635651
FAM83G Is a Novel Inducer of Apoptosis.
Okada J, Sunaga N, Yamada E, Saito T, Ozawa A, Nakajima Y, Okada K, Pessin JE, Okada S, Yamada M.Molecules. 2020 Jun 18;25(12):2810. doi: 10.3390/molecules25122810.PMID: 32570757.
Regulation of gene expression during the fasting-feeding cycle of the liver displays mouse strain specificity.
Chi Y, Youn DY, Xiaoli AM, Liu L, Pessin JB, Yang F, Pessin JE.J Biol Chem. 2020 Apr 10;295(15):4809-4821. doi: 10.1074/jbc.RA119.012349. Epub 2020 Feb 19.PMID: 32075912
SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.
Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, Ostenson CG, Kieffer TJ, Banks K, Pessin JE, Gaisano HY.JCI Insight. 2020 Feb 13;5(3):e129694. doi: 10.1172/jci.insight.129694.PMID: 32051343
Dapagliflozin Inhibits Cell Adhesion to Collagen I and IV and Increases Ectodomain Proteolytic Cleavage of DDR1 by Increasing ADAM10 Activity.
Okada J, Yamada E, Saito T, Yokoo H, Osaki A, Shimoda Y, Ozawa A, Nakajima Y, Pessin JE, Okada S, Yamada M.Molecules. 2020 Jan 23;25(3):495. doi: 10.3390/molecules25030495.PMID: 31979355
Analysis of FAM19A2/TAFA-2 function.
Okada J, Yamada E, Saito T, Ozawa A, Nakajima Y, Pessin JE, Okada S, Yamada M.Physiol Behav. 2019 Sep 1;208:112581. doi: 10.1016/j.physbeh.2019.112581. Epub 2019 Jun 17.PMID: 31220516
The subunit assembly state of the Mediator complex is nutrient-regulated and is dysregulated in a genetic model of insulin resistance and obesity.
Youn DY, Xiaoli AM, Kwon H, Yang F, Pessin JE.J Biol Chem. 2019 Jun 7;294(23):9076-9083. doi: 10.1074/jbc.RA119.007850. Epub 2019 Apr 26.PMID: 31028171
Lipolysis defect in white adipose tissue and rapid weight regain.
Kasher-Meron M, Youn DY, Zong H, Pessin JE.Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E185-E193. doi: 10.1152/ajpendo.00542.2018. Epub 2019 Apr 9.PMID: 30964706
Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease.
Abramowitz MK, Paredes W, Zhang K, Brightwell CR, Newsom JN, Kwon HJ, Custodio M, Buttar RS, Farooq H, Zaidi B, Pai R, Pessin JE, Hawkins M, Fry CS.Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1658-F1669. doi: 10.1152/ajprenal.00314.2018. Epub 2018 Oct 3.PMID: 30280599
SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy.
Feng D, Amgalan D, Singh R, Wei J, Wen J, Wei TP, McGraw TE, Kitsis RN, Pessin JE.J Clin Invest. 2018 Aug 31;128(9):3941-3956. doi: 10.1172/JCI99217. Epub 2018 Aug 13.PMID: 30102258
Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1.
Toledo M, Batista-Gonzalez A, Merheb E, Aoun ML, Tarabra E, Feng D, Sarparanta J, Merlo P, Botrè F, Schwartz GJ, Pessin JE, Singh R.Cell Metab. 2018 Aug 7;28(2):268-281.e4. doi: 10.1016/j.cmet.2018.05.023. Epub 2018 Jun 21.PMID: 29937374
The fructose-2,6-bisphosphatase TIGAR suppresses NF-κB signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC.
Tang Y, Kwon H, Neel BA, Kasher-Meron M, Pessin JB, Yamada E, Pessin JE.J Biol Chem. 2018 May 18;293(20):7578-7591. doi: 10.1074/jbc.RA118.002727. Epub 2018 Apr 12.PMID: 29650758
Mangiferin Accelerates Glycolysis and Enhances Mitochondrial Bioenergetics.
Liu Z, Apontes P, Fomenko EV, Chi N, Schuster VL, Kurland IJ, Pessin JE, Chi Y.Int J Mol Sci. 2018 Jan 9;19(1):201. doi: 10.3390/ijms19010201.PMID: 29315239
Differential activation of Fyn kinase distinguishes saturated and unsaturated fats in mouse macrophages.
Tarabra E, An Lee TW, Zammit VA, Vatish M, Yamada E, Pessin JE, Bastie CC.Oncotarget. 2017 Sep 21;8(49):86634-86645. doi: 10.18632/oncotarget.21258. eCollection 2017 Oct 17.PMID: 29156823
System-wide Benefits of Intermeal Fasting by Autophagy.
Martinez-Lopez N, Tarabra E, Toledo M, Garcia-Macia M, Sahu S, Coletto L, Batista-Gonzalez A, Barzilai N, Pessin JE, Schwartz GJ, Kersten S, Singh R.Cell Metab. 2017 Dec 5;26(6):856-871.e5. doi: 10.1016/j.cmet.2017.09.020. Epub 2017 Oct 26.PMID: 29107505
High frequency electrical stimulation of sciatic nerve enhances skeletal muscle autophagy in mice.
Yang YJ, Pessin JE, Wang L.Sheng Li Xue Bao. 2017 Aug 25;69(4):422-428.PMID: 28825100
ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes.
McKimpson WM, Zheng M, Chua SC, Pessin JE, Kitsis RN.Sci Rep. 2017 Aug 1;7(1):7019. doi: 10.1038/s41598-017-07107-w.PMID: 28765602
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α.
Song Z, Xiaoli AM, Zhang Q, Zhang Y, Yang EST, Wang S, Chang R, Zhang ZD, Yang G, Strich R, Pessin JE, Yang F.J Biol Chem. 2017 May 26;292(21):8918-8932. doi: 10.1074/jbc.M117.776229. Epub 2017 Mar 28.PMID: 28351837
MC4R-dependent suppression of appetite by bone-derived lipocalin 2.
Mosialou I, Shikhel S, Liu JM, Maurizi A, Luo N, He Z, Huang Y, Zong H, Friedman RA, Barasch J, Lanzano P, Deng L, Leibel RL, Rubin M, Nickolas T, Chung W, Zeltser LM, Williams KW, Pessin JE, Kousteni S.Nature. 2017 Mar 16;543(7645):385-390. doi: 10.1038/nature21697. Epub 2017 Mar 8.PMID: 28273060